U.S.A. develops " Keep fit through sports medicine "

U.S.A. develops " Keep fit through sports medicine "
In life, usually the fatter the more lazy the fat personage is, such vicious circle, make many people's weight unable to control once began. American researchers develop a new medicine, test on mouse, find, it not only can inhibit the appetite, can also stimulate them to move more.
Eat and move more few
The researchers of medical college of Harvard University are to one group " Inadequate natural endowment " Mouse go on experiment. Researchers are while cultivating them " Have moved some tricks " ,Make in mouse's body or lack a kind of hormone which controls the appetite " Thin and plain" (also call thin voxel) ,Whether or unable to be thin correctly usually reacts. So these mice are fat seriously, still suffer from diabetes.
Researcher let mouse eat tablet any more, activate the intersection of P O M C and neuronal receptor, enable it to tight to usually react, and then inhibit the appetite.
The experimental result reveals, though the bodily form of these mice is too fat and clumsy to move, sluggish, but their amount of exercise doubles before the experiment. They return " Conscientious" Reduce and take in calorie and invite 30, the weight thereupon slightly drops too.
What made people surprised even more is, though the mouse has not changed the eating habit, the weight has not obviously dropped either, but their blood glucose level has already been returned to the normal value.
The intersection of U.S.A. and " the cell - supersession " that publish June monthly magazine publish the research report.
Magical and " thin and plain "
It is thin and plain in researchers are through regulating mouse's body, make them eat and move more few, thin usually performs meritorious deeds never to be obliterated.
Thin and plain can produce function on the hypothalamic part in the central nervous system. And the hypothalamic part contains two kinds of neurons that can produce opposing reaction, including inhibiting P O M C neuron of the appetite and promoting A g R P neuron of the appetite. Thin and plain realizes energy balance through acting on these two kinds of neurons.
In mouse's experiment, researchers only activate thin plain neuronal function to P O M C, thus inhibit mouse's appetite and get up to the weight-reducing result.
Britain " daily post " invokes one of the researchers, endocrinologist Christian to say more than Yoel and Bake's words on the 2nd: "Only act on these a handful of neurons, it is enough to come into force. "
Research find pass, act on hypothalamic too, thin to still can control the intersection of blood glucose and level while being plain still before, influence people's activity desire.
Need time
Though the research results bring a dawn for the weight-reducing personage, researchers say, it is still at the starting stage to study, this method moves towards the market from the laboratory it needs time.
Researchers say frankly, study for the moment and is limited to the mouse onlied, generalize to the mankind this method still for annual time. But they believe this will drive and study in the future. "This lets us further develop and impel fat people to thirst for the medicine of sports, "Say more than Yoel and Bake.
In addition, researcher to tight and plain and P O M C still limited in neuronal cognition at present. For example, do not know for the moment whether this research is suitable for the thin mouse, function mechanism to other organs of P O M C neuron is not analysed and explained yet, researchers do not know either it is that it influences the blood glucose level which plants the neuron in the brain mound on earth, wait a moment.
However, seeing that the fat phenomenon grows in intensity, this research still belongs to big progress in the weight-reducing respect. " the daily post " say people are fat will it be about 1/4 year such as Britain now, the expert believes, if people do not change the eating habit or increase the amount of exercise, there may be over half British adults by 2050 and reach the fat, and this will make the number of the infected of diseases such as heart disease, apoplexy, diabetes, cancer,etc. increase sharply.
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