U.S.A. find take a sniff at sheath cell originate from expected to use for the nerve repair and transplant newly

U.S.A. find take a sniff at sheath cell originate from expected to use for the nerve repair and transplant newly
Organize the report on November 15 of network according to the American physicist, take a sniff at sheath cells (OECs) Wrapped up the capsule shielded outside the olfactory nerve fibre, over the last 25 years, people have been thinking and taking a sniff at sheath cells all the time that has been formed by membrane in the nose, but a new research of British scientist reveals, taking a sniff at sheath cells has different origins.
If will take a sniff at sheath cells to transplant to the spinal damaged, can promote the nerve to repair, support the regeneration of central nervous system, this new discovery has offered more reliable resources for treating the spinal to damage. This research is linked the fund subsidy of health fund and Isaac and Newton by Britain, issue U.S.A. this week in result of study >Have.
Theoretically, can utilize inner membrane that patients took out in the nose to organize, sprout in training wares and take a sniff at sheath cells, then transplanting it to spinal damaged can be promoted the nerve to repaired, do not need to worry about any row of different responses. But there is too less cell quantity that this kind of method is received, can't offer enough sources for treating.
CrayResearch that thesis main author, British Cambridge University develop and neural science is biological Dr. Bake says : " Taking a sniff at sheath cells too few in the membrane in the nose, among them still wrapping up the peripheral nerve fibre, and fiber these and it takes a sniff at sheathes to be very similar in cell, to promote the spinal repair and matter results. It is very difficult to purify in the membrane out enough taking a sniff at sheath cells from the nose, carry on the effective transplantation treatment. "
And this discovers newly, it is the same to take a sniff at sheath cells as other cells which is wrapping up the nerve fibre, stem from one call neural ridge cell (neural crest cells) Embryo stem cell . In order to find taking a sniff at the origin of sheath cells, researchers use green fluorogenic albumen mark embryo's nerve ridge cells, make it can give out green fluoro under the circumstances that ultraviolet ray shines. Utilizing genetic technology, researchers transplant the neural ridge cells of the green fluorogenic albumen mark in the embryos of chicken and little mouse, neural ridge cell and offspring's cell can express the green fluorogenic albumen in this way, change that can track neural ridge cells take place with neural development of the sense of smell by this. Through analyzing the embryo slices, these green cells with molecule mark are wrapping up a bunch of olfactory nerve fibres, that is to say they really take a sniff at sheath cells.
And the intersection of adult and skin and mao contain neural the intersection of ridge and cell, for train in a large amount, take a sniff at the intersection of sheath and cell, offer possible in laboratory this in the pocket. Dr. Bake says, needs next to study how to change these stem cells into taking a sniff at sheath cells, and study how normal and open this course is in embryo's development. This may spend time of a few years, but discovery of us offer Singapore side for purifying and taking a sniff at sheath cells to. (Chang LiJun )
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