The U.S.A. one be lasted stated 4 genotype third liver virus.. 's general knowledge
( Journal of Clinical Gastroenterology 2004; 38(1) : 68-71)
December 25 because third liver virus genotype can influence the response of virus treatment of face-off, therefore have important clinical meanings. 4 genotypes HCV of U.S.A. are rare, few disclose the materials and canvass 4 genotypes HCV and infect patient's response of the treatment too. For this reason, Andre C of St.Louis university medical college. Dr. LyraHaving appraised with U.S.A. 4 genotypes HCV infect the relevant epidemiology factored, and investigate a patient unites the therapeutic response rate with favourable Palestinian Waring to interferon .
Researchers have consulted all liver disease doctors of the department where one stays, obtain information of 4 genotype HCV patients who once treated. They search nearly 40 months such as hospital such as university such as St.Louis ' From 1999 to 2002) The computer database that came, find 20 4 genotype HCV patients together. They still carry on reviewing chart analysis to the materials, information of checking, opposing the response of virus treatment in the demography, dangerous factor, basic laboratory infected to put the patient in order etc..
The result reveals, 14 (70%) The patient has dangerous factor exposed to HCV: 12 patients take drug illegally history, 3 patients have history of blood transfusion, a patient has two dangerous factors at the same time. In 20 patients, there are 3 or 4 fibers. 17 patients treat, 14 patients among them finish treating, 10 patients for the persons who reply continuously.
Lyra Dr. think, the same as other genotypes HCV, the intersection of majority and 4 the intersection of genotype and HCV of U.S.A. infect patient, take drug, take place, infect through vein. The patient's liver pathological change is usually light to intermediate, 59% of the patients jointly treat and produce lasting virology to reply to interferon and favourable Palestinian Waring.
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