U.S.A. warns - -The early newborn baby uses one gram of strength sesame to present the serious health problem

U.S.A. warns - -The early newborn baby uses one gram of strength sesame to present the serious health problem
It is March 8 2011 year, Food and Drug Administration release of American information,it is open to declare at the Customs at Lip river rolls of Wei of using /profit last oral liquid (goods name Wei: Gram of strength sesame Kaletra) Treating the early newborn baby is reported that the serious health problem appears.
Grams of strength sesame oral liquid a antiviral medicine, with resist against duplicate the intersection of virus and medicine, use for, born 14 day (early newborn baby or not getting mature jointly while being other) Or the intersection of pediatrics and patient and HIV-1 of adult of the above infect. Take used for treating HIV and infecting to resist against duplicate the intersection of virus and medicine, can cure, infect, but the children who can help HIV-1 to infect keep healthier state with the adult within long time. It is used in less than the baby's security and effective dose of 14 days not to confirm one gram of strength sesame oral liquid yet at present.
FDA check grams of the intersection of strength and bad the intersection of incident and report merchandize, of sesame oral liquid under September to will it be September 2010, 2000, find 10 neonates present the incident which jeopardize the life, these 10 majority are an early newborn baby ' Have 8 neonate born when for 28 week to about 35 week the intersection of fetus and age range in the 10) ,And taken one gram of strength sesame oral liquid. The serious bad reaction incident reported includes: The heart is toxic ' Getting complete atrio-ventricular block, aroused in interest to relax myocardium disease) Lactic acid acidosis, acute kidney declined, central nervous system inhibiting and respiratory system complication.
FDA proposes to the doctor:
Up to the intersection of correction and age such as child for 42 week ' From sum of day age of reality after Zhou Ling and foetus given birth to of the end of mother the foetus) Should prevent the neonate from using one gram of strength sesame oral liquid before at least 14 days after with borning.
Because of the toxicity that may be produced, should use one gram of strength sesame oral liquid immediately after preventing the early newborn baby from being born in. Likewise, should prevent from less than 14 day getting mature to use grams of the intersection of force and sesame oral liquid. It is used in this kind of group's security and validity dosage to confirm one gram of strength sesame oral liquid yet.
If doctor think baby use grams of the intersection of strength and sesame oral liquid it treats whom HIV infects to be benefited to greater than his potential risk immediately born, should monitor neonatal serum and permeate pressing and rising of serum skin anhydride tightly, and the toxicity related to gram of strength sesame oral liquid, comprising: With or noble-minded and unwilling to swim with the tide to permeate, press in acidosic blood with lactic acid nature and the intersection of kidney and toxicity, central nervous system inhibit from Epilepsy break out, the intersection of tension and fail, arrhythmia, the intersection of electroencephalogram and change and haemolysis.
Should calculate children use the dosage of one gram of strength sesame oral liquid according to the weight or area of body surface, in order to prevent the dosage from being insufficient or exceed the dosage of adult that recommends.
Should consider alcohol and the third total amount of two alcohol included in all medicines that accept to the pediatrics patient of 6 months for 14 days, in order to avoid coming from the toxicity that these adjuvants produce.
As to the premature delivery neonate, it may be even fatal seriously that the toxicity of one gram of strength sesame oral liquid reacts, and may be considered by mistake to be neonatal septicaemia. For presenting this kind of situation, the key should stop medicines immediately.
The editor briefs on: Lip river rolls of Wei profit that ask oral liquid Wei that, goods call grams of the intersection of force and sesame, produce by the company of Abbott Laboratories, will be sanctioned applying to AIDS Line two treatment of our country in 2008.
(American Food and Drug Administration website)
(detailed information please see the newspaper network of the health " The medical equipment of medicine warns information " Special column)
Sponsor: Newspaper office of the health
Do jointly: National food medicines supervise administration bureau medicines appraising the centre
National medicines bad reaction monitoring center
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