The American scientist finds - -Genetic _'s general knowledge which cause rare hereditary hypertension

The American scientist finds - -Genetic _'s general knowledge which cause rare hereditary hypertension
Yale University releases " press Communique " and claims, the researchers of this university have found two mutation genes that can cause a kind of rare hereditary hypertension, thus has opened up the road in order to treat the essential hypertension.
Science of heredity of Yale University School of Medicine, clinical practice and molecule biophysics professor, main researcher Lifton doctor are called, deserve discovering in the unknown biochemical mechanism correlated with regulating blood pressure, this result makes to develop new medicine that can influence the function of this mechanism, thus treat hypertension and congestive heart to decline, become possible effectively. This article is issued Science published on August 10.
Lifton group determines from 20 families of the whole world that a kind of rare hypertension appears by analytic approach of science of heredity, called the false aldosterone and reduced the disease 2 type (PHA2) Key cause of disease. PHA2 can cause hypertension, can reduce the ability to remove potassium and hydrogen ion in the body too. Researchers find 2 genes which cause this disease belong to a new protein family, this kind of protein can regulate the activity of other albumens through adding the phosphate group. These 2 proteins lie about regulating the position of sodium, potassium and pH in the kidney, reabsorption to sodium that they strengthen the kidney and reducing the discharge of potassium and hydrogen.
Lifton claims, already thinking to relate to common essential hypertension early in the morning of 2 mutation genes, the common variation of this gene is probably a cause of disease of causing the masses of crowd's essential hypertension too.
Lifton seminar and Framingham heart seminar are investigating these newly discovered function played in general crowd's hypertension have illness coming on of gene jointly. He says, these new main causes of disease of this kind of common disease of strengthening understanding of result of study, and open up new therapeutic method.
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